Bucknor 2021


Year: 2021

Title: Disparities in PET imaging for prostate cancer at a tertiary academic medical center

Country: United States

Age: Adult Only

Sex: Male

Population: Multiple Groups

Care Setting: Outpatient Ambulatory and Primary Care

Clinical Setting: Cancer Care

Data Level: Single Institution

Data Type: EHR

Data Source: Local data

Conclusion: Disparities In Some Minority Groups

Health OutComes Reported: No

Mitigation: No

Free Text Conclusion: Black patients were less likely to have 68-Ga-PSMA-11 PET imaging studies for prostate cancer than non-Hispanic White patients, which offers better detection rates compared with 18F-fluciclovine.

Abstract: The purpose of this study was to evaluate differences between patients receiving 18F-fluciclovine and 68Ga-prostate-specific membrane antigen (68Ga-PSMA-11) for biochemically recurrent prostate cancer at a tertiary medical center. METHODS: All 18F-fluciclovine and 68Ga-PSMA-11 PET studies performed at the University of California San Francisco from October 2015 to January 2020 were reviewed. Age, race/ethnicity, primary language, body mass index, insurance type, and home address were obtained through the electronic medical record. A logistic regression model was used to evaluate the predictor variables. RESULTS: In total, 1,502 patients received 68Ga-PSMA-11 and 254 patients received 18F-fluciclovine. Black patients had increased odds of receiving imaging with 18F-fluciclovine versus 68Ga-PSMA-11 compared with non-Hispanic White patients (odds ratio, 3.88; 95% CI, 1.90-7.91). There were no other statistically significant differences. CONCLUSION: In patients receiving molecular imaging for prostate cancer at a single U.S. tertiary medical center, access to 68Ga-PSMA-11 for Black patients was limited, compared with non-Hispanic White patients, by a factor of nearly 4.