(WRAP) Wisconsin Registry for Alzheimer’s Prevention

The PI of this project is: Sterling Johnson, PhD

This project is funded by: NIH

The term of this project is: August 2018 to March 2023

The number of subjects scanned during this project is: 150

The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is a longitudinal study designed to characterize cognitive changes and identify predictive biomarkers, health and lifestyle features that confer risk and resilience to Alzheimer’s Disease (AD). The ability to predict AD risk from biomarker and cognitive profiles obtained in midlife is a prerequisite for development and evaluation of disease-modifying interventions in asymptomatic populations. Similarly, identifying health, lifestyle and genetic factors that confer susceptibility or resilience to AD is critical to understanding the disease course. WRAP participants will be invited to undergo CSF, MRI and [F-18]MK6240 and [C11]PiB PET scans.