Elizabeth Sadowski’s Study on ORADS Published in JAMA  

Posted on July 2022

Elizabeth Sadowski, MD recently had a study published in the Journal of the American Medical Association called, “Diagnostic Performance of The Ovarian-Adnexal Reporting and Data System Ultrasound Risk Score in US Women.” Dr. Sadowski served as the senior author and collaborated with former UW fellow, Akshya Gupta, MD (University of Rochester), and Priyanka Jha, MD (University of California, San Fransisco). 

This study assessed nearly a thousand lesions on ultrasound from five participating academic centers from the East Coast to the West Coast. The team concluded that “O-RADS US risk stratification system is a scoring algorithm that can be applied to a non-selected population in United States and yields an estimated risk of malignancy for lesions which falls within the expected range as published by the ACR O-RADS US committee. O-RADS US 4 was the optimum cut off for the diagnosis of cancer, with a sensitivity and specificity for malignancy at 90.6% and 81.9%, a PPV of 31.4% and NPV of 99.0%.” 

Dr. Sadowski adds, “The O-RADS US risk score can be used in the assessment and reporting of adnexal lesions across all practice settings and regardless of expertise. This benefits women by allowing clinicians to care for women in a more consistent and data driven fashion – improving their outcomes through imaging.” 

The results from this study have been featured on Aunt Minnie and the American College of Radiology’s newsletter. You can read the original article here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2793172